Association of inflammation, dyslipidemia, obesity and physical activity status in children

نویسندگان

  • Juliano Magalhães Guedes
  • José Bontempo
  • Mamêde Neto
  • Alynne Christian Ribeiro Andaki
  • Patrícia Feliciano Pereira
  • Michelle Dias de Oliveira
  • Roberto Sousa Dias
  • Sérgio Oliveira de Paula
  • Antônio José Natali
  • Alexandre de Paula Rogério
  • Edmar Lacerda Mendes
چکیده

–The aim of this study was to verify the association between inflammatory biomarkers, dyslipidemia, obesity and physical activity status in 10-years old children. Ninety-four children participated in this study and were classified into eutrophic (n=36), overweight (n=34) or obese (n=24) according to their body mass index (BMI). The genic expression of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and chemokine C-C motif ligand 2 (CCL-2) mRNA; the serum concentration of high-density lipoprotein cholesterol (HDL-c) and triglycerides; BMI, percentage of body fat (% BF) and waist circumference; and the number of steps per day were determined. The expression of IL-6, TNF-α and CCL-2 were associated (p < 0.05) positively with serum triglycerides, BMI, % BF and waist circumference, and negatively with serum HDL-c. No association (p > 0.05) between pro-inflammatory biomarkers and number of steps per day was found.

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تاریخ انتشار 2016